A workshop organized for and by ATMP operators, technicians and other experts handling, developing and/or producing ATMPs​. The goal of the workshop was to exchange experiences, common practices and challenges, stimulate interaction and foster collaborations​.

A summary of the key take aways will be shared with the attendees. Contact info@dare-nl.nl if you are a DARE-NL member and would like to receive the summary.

Find below the event program and pictures.

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Program:

09.00 – 09.30      Welcome with coffee & tea

Session 1: Disinfection

09.30 – 10.15    Karin Hanraets (STAXS): Training on bringing materials into the cleanroom

10.15 – 10.30     Anouk Donners (UMCU): Training on environmental monitoring

10.30 – 11.30     Break-out session, topics:

• procedures for difficult materials
• environmental monitoring
• cross-contamination and line clearance
• gowning

11.30 – 12.30     Lunch

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Session 2: Cell culture methods

12.30 – 12.45     Cor Berrevoets (EMC): Current manual culture and harvesting procedure

12.45 – 13.30     Maaike van Zon & Saskia Scheij (NKI): Transition to upscaling and automated process​ on Xuri Cell Expansion System

13.30 – 14.00     Sabrina Veld (LUMC) & Annet Daudeij (UMCU): Productions ​on the CliniMACS Prodigy

14.00 – 14.30     Gaby Rijsdijk (Sanquin) & Niek van der Zee (AUMC): Productions on the Cocoon Platform ​

14.30 – 15.00     Break​

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Session 3: QC analysis

15.00 – 16.00     Break-out session, topics:

• cell count and viability
• characterization assays (e.g. phenotype, flow cytometry)
• functional assays (incl potency)
• microbiology & virus assays (contaminants, virus determinants)

16.00 – 16.15     Concluding remarks

16.15 – 17.00     Drinks​